Inhibition by melatonin of prostaglandin synthesis in hypothalamus, uterus and platelets
Melatonin (0.01 uM concentrations or greater) depressed the spontaneous motility of the uterus of virgin ovariectomized rats (a prostaglandin-related phenomenon) as well as the release of PGE from rat medial basal hypothalamus in vitro. In another model system for PG synthesis, i.e. the human platel...
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| Autores principales: | , , , , , |
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| Formato: | JOUR |
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00653446_v29_nC_p147_Gimeno |
| Aporte de: |
| Sumario: | Melatonin (0.01 uM concentrations or greater) depressed the spontaneous motility of the uterus of virgin ovariectomized rats (a prostaglandin-related phenomenon) as well as the release of PGE from rat medial basal hypothalamus in vitro. In another model system for PG synthesis, i.e. the human platelets, melatonin (0.1 mM) inhibited ADP-induced platelet aggregation. © 1981. |
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