Tetraethyl vinylidenebisphosphonate: A versatile synthon for the preparation of bisphosphonates

Tetraethyl vinylidenebisphosphonate is a versatile synthetic intermediate that allows access to a variety of highly functionalized compounds bearing the bisphosphonic moiety. As an electron-deficient alkene, this compound is able to undergo conjugate addition with a variety of reagents including str...

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Detalles Bibliográficos
Autor principal:	Rodriguez, J.B.
Formato:	JOUR
Materias:	1 3-dipolar cycloadditions bisphosphonates Michael additions tetraethyl vinylidene bisphosphonate Amines Chemical compounds Cycloaddition Nitrogen oxides Nucleophiles Olefins Organometallics 1 ,3-dipolar cycloadditions Bisphosphonates Cycloadditions Functionalized compounds Michael addition reactions Rearrangement reactions Synthetic intermediates Addition reactions amine azide azomethine ylide bisphosphonic acid derivative nitrile oxide nitrone derivative phosphonic acid derivative phosphorus tetraethyl vinylidenebisphosphonate thiol unclassified drug chemical structure concentration (parameters) cyclization cycloaddition enantioselectivity epoxidation Michael addition oxidation reduction reaction physical chemistry review stereochemistry structure analysis
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00397881_v46_n9_p1129_Rodriguez
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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