Synthesis and cytotoxic evaluation of four new 6E-hydroximinosteroids

Four new 6E-hydroximinosteroids (1, 2a, 3 and 4) have been synthesized from the corresponding ketones, 2β,3β-dihydroxy-5α-cholestan-6-one (5), 2α,3α-dihydroxy-5α-cholestan-6-one (6), 2β,3α-dihydroxy-5α-cholestan-6-one (7) and 2β,3α- dihydroxy-5α-cholestan-6-one-disulfate (8). The cytotoxic activity...

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Detalles Bibliográficos
Autores principales:	Richmond, V., Careaga, V.P., Sacca, P., Calvo, J.C., Maier, M.S.
Formato:	JOUR
Materias:	Hydroximinosteroids Prostate cancer Sulfated steroids Synthesis 6e hydroximinosteroid corticosteroid derivative unclassified drug 6E-hydroximinosteroid steroid article cytotoxicity drug synthesis human human cell male nonhuman prostate carcinoma drug screening electrospray mass spectrometry infrared spectroscopy proton nuclear magnetic resonance synthesis tumor cell line Cell Line, Tumor Drug Screening Assays, Antitumor Humans Male Proton Magnetic Resonance Spectroscopy Spectrometry, Mass, Electrospray Ionization Spectroscopy, Fourier Transform Infrared Steroids
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_0039128X_v84_n_p7_Richmond
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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