New C-secosteroids from the gorgonian Tripalea clavaria

Seven new C-secosteroids were isolated from the gorgonian Tripalea clavaria collected from the South Atlantic. These compounds have a Δ5, 9,11-secosteroid nucleus together with a 22S hydroxyl group. The absolute configuration of the 22-hydroxyl group was determined with the help of COSY spectra of t...

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Detalles Bibliográficos
Autores principales: Rodríguez Brasco, M.F., Genzano, G.N., Palermo, J.A.
Formato: JOUR
Materias:
Gorgonian
Marine sterols
Secosteroids
Tripalea clavaria
3beta acetoxy 11,21,22 trihydroxy 9,11 secocholest 5 en 9 one
3beta acetoxy 11,22 dihydroxy 9,11 secocholest 5 en 9 one
3beta acetoxy 11,22 dihydroxy 9,11 secoergost 5,24(28) dien 9 one
3beta,11 dihydroxy 9,11 seco 24 norcholest 5 en 9 one
3beta,11,21,22 tetrahydroxy 9,11 secocholest 5 en 9 one
3beta,11,22 trihydroxy 9,11 secocholest 5 en 9 one
3beta,11,22 trihydroxy 9,11 secocholest 5,24 dien 9 one
secosteroid
unclassified drug
antibiotic sensitivity
antimicrobial activity
article
carbon nuclear magnetic resonance
coelenterate
drug isolation
drug structure
nonhuman
proton nuclear magnetic resonance
Staphylococcus aureus
Animals
Anthozoa
Anti-Bacterial Agents
Antibiotics, Antifungal
Bacillus subtilis
Botrytis
Candida albicans
Escherichia coli
Magnetic Resonance Spectroscopy
Molecular Structure
Gorgonia
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0039128X_v72_n14_p908_RodriguezBrasco
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:Seven new C-secosteroids were isolated from the gorgonian Tripalea clavaria collected from the South Atlantic. These compounds have a Δ5, 9,11-secosteroid nucleus together with a 22S hydroxyl group. The absolute configuration of the 22-hydroxyl group was determined with the help of COSY spectra of the Mosher esters of the compounds. © 2007 Elsevier Inc. All rights reserved.

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