A Positive Influence of Frequency on the Inotropic Response of Isolated Rat Atria to Certain Adrenergic Amines. Effects of Cocaine and U-0521 (3′, 4′-Dihydroxy-2-methyl Propiophenone)

The effects of several inotropic interventions on the isometric developed tension (IDT) of isolated left rat atrium, electrically driven at several frequencies were investigated. The experimental stimulating procedure allowed the attainment at all the rates tested (25, 50, 100, and 200 per min), sim...

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Detalles Bibliográficos
Autores principales: Sterin-Borda, L., Gimeno, M.F., Borda, E.S., Gimeno, A.L.
Formato: JOUR
Materias:
calcium chloride
cocaine
isoprenaline
noradrenalin
phenylephrine
dihydroxy 2 methylpropiophenone
drug comparison
drug metabolism
drug potentiation
heart left atrium
heart rate
heart ventricle isometric contraction
in vitro study
inotropism
presynaptic membrane
rat
tension
theoretical study
Animal
Calcium Chloride
Cocaine
Drug Interactions
Electric Stimulation
Heart Rate
In Vitro
Isoproterenol
Male
Myocardial Contraction
Norepinephrine
Phenylephrine
Propiophenones
Rats
Sympathomimetics
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00379727_v156_n2_p315_SterinBorda
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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