Mixed nicotinic-muscarinic properties of the α9 nicotinic cholinergic receptor

The rat α9 nicotinic acetylcholine receptor (nAChR) was expressed in Xenopus laevis oocytes and tested for its sensitivity to a wide variety of cholinergic compounds. Acetylcholine (ACh), carbachol, choline and methylcarbachol elicited agonist-evoked currents, giving maximal or near maximal response...

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Detalles Bibliográficos
Autores principales: Verbitsky, M., Rothlin, C.V., Katz, E., Belén Elgoyhen, A.
Formato: JOUR
Materias:
Cochlea
Hair cells
Ion channels
Muscarinic receptors
Neurotransmitter receptors
Nicotinic receptors
acetylcholine
atropine
bethanechol
carbachol
choline
cholinergic receptor stimulating agent
cytisine
dicholine suberate
dihydro beta erythroidine
epibatidine
gallamine
ion channel
mecamylamine
methylcarbachol
methyllycaconitine
muscarine
muscarinic agent
muscarinic receptor
muscarinic receptor blocking agent
neurotransmitter receptor
nicotine
nicotinic agent
nicotinic receptor
nicotinic receptor blocking agent
phenyltrimethylammonium
pilocarpine
pirenzepine
tetramethylammonium
[4 [(3 chlorophenyl)carbamoyloxy] 2 butynyl]trimethylammonium
animal cell
binding site
cochlea
controlled study
drug receptor binding
electrophysiology
hair cell
nonhuman
oocyte
priority journal
review
Xenopus laevis
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00283908_v39_n13_p2515_Verbitsky
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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