Curcumin inhibits the growth, induces apoptosis and modulates the function of pituitary folliculostellate cells

The polyphenol curcumin (diferuloylmethane) is the active componenet of the spice plant Curcuma longa and has been shown to exert multiple actions on mammalian cells. We have studied its effect on folliculostellate (FS) TtT/GF mouse pituitary cells, representative of a multifunctional, endocrine ina...

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Detalles Bibliográficos
Autores principales: Schaaf, C., Shan, B., Onofri, C., Stalla, G.K., Arzt, E., Schilling, T., Perone, M.J., Renner, U.
Formato: JOUR
Materias:
Apoptosis
Cell cycle
Curcumin
Folliculostellate pituitary cells
Interleukin-6
Nuclear factor-κB
Proliferation
Tlr4
Vascular endothelial growth factor
7 aminodactinomycin
agar
caspase 3
curcumin
cyclin D1
DNA
endotoxin
fluorescein isothiocyanate
immunoglobulin enhancer binding protein
interleukin 6
lipocortin 5
messenger RNA
protein bcl 2
toll like receptor 4
vasculotropin A
angiogenesis
animal cell
antineoplastic activity
apoptosis
article
cell culture
cell cycle arrest
cell cycle G2 phase
cell cycle M phase
cell death
cell growth
cell proliferation
cell type
colony formation
controlled study
cytokine production
cytokine release
DNA fragmentation
drug inhibition
endocrine cell
fluorescence activated cell sorting
growth inhibition
hypophysis cell
immune response
immunohistochemistry
monolayer culture
nonhuman
nucleotide sequence
pituitary folliculostellate cell
priority journal
protein cleavage
protein expression
receptor down regulation
RNA synthesis
Animals
Anti-Inflammatory Agents, Non-Steroidal
Cell Cycle
Cell Division
Cell Line, Tumor
Male
Mice
Pituitary Gland, Anterior
Pituitary Neoplasms
Rats
Rats, Sprague-Dawley
RNA, Messenger
Vascular Endothelial Growth Factor A
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00283835_v91_n2_p200_Schaaf
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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