GABAB receptors in anterior pituitary cells: Mechanism of action coupled to endocrine effects

The activation of pituitary GABAB receptors by the specific agonist baclofen inhibits pituitary hormone secretion in vitro. Here we studied the mechanism of action of GABAB receptors in rat adenohypophysis. Anterior pituitary cells were obtained by trypsinization and were either plated for hormonal...

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Detalles Bibliográficos
Autores principales:	Lux-Lantos, V., Becú-Villalobos, D., Bianchi, M., Rey-Roldán, E., Chamson-Reig, A., Pignataro, O., Libertun, C.
Formato:	JOUR
Materias:	Calcium Cyclic AMP G proteins GABAB receptors Gamma-aminobutyric acid Gamma-aminobutyric acid receptors Gonadotropin-releasing hormone Gonadotropins Prolactin Thyrotropin-releasing hormone 2 hydroxysaclofen 4 aminobutyric acid B receptor 4 aminobutyric acid B receptor blocking agent baclofen barium calcium channel calcium ion cyclic AMP dopamine forskolin fura 2 acetoxymethyl ester gonadorelin guanine nucleotide binding protein hypophysis hormone luteinizing hormone nifedipine pertussis toxin potassium channel blocking agent prolactin protirelin tetrylammonium trypsin verapamil adenohypophysis animal cell animal tissue article calcium cell level controlled study female hypophysis cell luteinizing hormone release nonhuman presynaptic nerve priority journal proestrus prolactin release rat receptor binding Animals Baclofen Barium Compounds Calcium Channel Blockers Cells, Cultured Chlorides Dopamine Female Forskolin Luteinizing Hormone Pertussis Toxin Pituitary Gland, Anterior Potassium Channel Blockers Potassium Chloride Proestrus Rats Receptors, GABA-B Tetraethylammonium Thyrotropin-Releasing Hormone Virulence Factors, Bordetella
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00283835_v73_n5_p334_LuxLantos
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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