Local frustration around enzyme active sites
Conflicting biological goals often meet in the specification of protein sequences for structure and function. Overall, strong energetic conflicts are minimized in folded native states according to the principle of minimal frustration, so that a sequence can spontaneously fold, but local violations o...
Guardado en:
| Autores principales: | Freiberger, M.I., Brenda Guzovsky, A., Wolynes, P.G., Gonzalo Parra, R., Ferreiro, D.U. |
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| Formato: | JOUR |
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00278424_v116_n10_p4037_Freiberger |
| Aporte de: |
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