Extracellular DNA: A major proinflammatory component of Pseudomonas aeruginosa biofilms

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We previously demonstrated that extracellular bacterial DNA activates neutrophils through a CpG- and TLR9-independent mechanism. Biofilms are microbial communities enclosed in a polymeric matrix that play a critical role in the pathogenesis of many infectious diseases. Because extracellular DNA is a...

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Detalles Bibliográficos
Autores principales: Fuxman Bass, J.I., Russo, D.M., Gabelloni, M.L., Geffner, J.R., Giordano, M., Catalano, M., Zorreguieta, Á., Trevani, A.S.
Formato: JOUR
Materias:
CD11b antigen
CD18 antigen
CD66b antigen
deoxyribonuclease I
DNA
interleukin 1beta
interleukin 8
lymphocyte antigen
unclassified drug
bacterial DNA
cytokine
article
bacterial strain
biofilm
controlled study
cytokine release
degradation
extracellular matrix
human
leukocyte activation
nonhuman
phagocytosis
priority journal
Pseudomonas aeruginosa
upregulation
biosynthesis
chemistry
confocal microscopy
extracellular fluid
growth, development and aging
immunology
metabolism
microbiology
neutrophil
physiology
Biofilms
Cytokines
DNA, Bacterial
Extracellular Fluid
Humans
Microscopy, Confocal
Neutrophil Activation
Neutrophils
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00221767_v184_n11_p6386_FuxmanBass
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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