Mevalonate dependency of the early cell cycle mitogenic response to epidermal growth factor and prostaglandin F2α in Swiss mouse 3T3 cells
Lovastatin (LOV), a hydroxy‐methylglutaryl‐coenzyme A (HMGCoA) reductase competitive inhibitor, blocks epidermal growth factor (EGF)— or prostaglandin F2α (PGF2α)—induced mitogenesis in confluent resting Swiss 3T3 cells. This inhibition occurs even in the presence of insulin, which potentiates the a...
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| Autores principales: | Ortiz, M.B., Goin, M., de Alzaga, M.B.G., Hammarstrom, S., de Asua, L.J. |
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| Formato: | JOUR |
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00219541_v162_n1_p139_Ortiz |
| Aporte de: |
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