Synaptic control of mRNA translation by reversible assembly of XRN1 bodies

Repression of mRNA translation is linked to the formation of specific cytosolic foci such as stress granules and processing bodies, which store or degrade mRNAs. In neurons, synaptic activity regulates translation at the post-synapse and this is important for plasticity. N-methyl-D-aspartate (NMDA)...

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Detalles Bibliográficos
Autores principales: Luchelli, L., Thomas, M.G., Boccaccio, G.L.
Formato: JOUR
Materias:
P body
RNA granule
Stress granule
Synapse
XRN1
exoribonuclease
messenger RNA
metabotropic receptor
n methyl dextro aspartic acid
synapsin
unclassified drug
XRN1 protein
DNA binding protein
n methyl dextro aspartic acid receptor
Xrn1 protein, mouse
animal experiment
animal tissue
Article
cell body
cellular distribution
controlled study
dendrite
dendritic spine
hippocampal CA1 region
hippocampal CA3 region
hippocampal neuronal culture
immunofluorescence
nonhuman
priority journal
protein localization
protein processing
protein synthesis
rat
RNA translation
synapse
Western blotting
amino acid sequence
animal
cell culture
cell organelle
gene expression regulation
genetics
metabolism
molecular genetics
mouse
nerve cell
Sprague Dawley rat
Amino Acid Sequence
Animals
Cells, Cultured
DNA-Binding Proteins
Exoribonucleases
Gene Expression Regulation
Mice
Molecular Sequence Data
Neurons
Organelles
Protein Biosynthesis
Rats, Sprague-Dawley
Receptors, Metabotropic Glutamate
Receptors, N-Methyl-D-Aspartate
RNA, Messenger
Synapses
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00219533_v128_n8_p1542_Luchelli
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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