Synthesis and antitumor activity of anthracycline disaccharide glycosides containing daunosamine

Daunosamine, as its 4-O-acetyl-3-N-trinfluoroacetyl glycosyl chloride derivative (1b), has been coupled α-L-glycosidically to the 3- and 4-mono-O-acetyl derivatives of L-rhamnal to afford disaccharide glycal derivatives, whose conversion into the corresponding 2-deoxyglycosides by sequential alkoxyi...

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Detalles Bibliográficos
Autores principales:	Horton, D., Priebe1, W., Sznaidmanc, M.L., Varela, O.
Formato:	JOUR
Materias:	anthracycline derivative daunosamine antineoplastic activity article chemical structure drug synthesis human human cell priority journal
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00218820_v46_n11_p1720_Horton
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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