Synthesis of (2′s)-2′-deoxy-2′-C-methylpurine nucleosides and their phosphoramidites

We describe the stereoselective synthesis of (2′S)-2′-deoxy-2′-C-methyladenosine (12) and (2′S)-2′-deoxy-2′-C-methylinosine (14) as well as their corresponding cyanoethyl phosphoramidites 16 and 19 from 6-0-(2,6-dichlorophenyl)inosine as starting material. The methyl group at the 2′-position was int...

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Autores principales: Caballero, G., Gallo, M., Montserrat, J.M., Iribarren, A.M.
Formato: JOUR
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Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0018019X_v85_n5_p1284_Caballero
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