11β-Hydroxysteroid dehydrogenase type 2 complementary deoxyribonucleic acid stably transfected into Chinese hamster ovary cells: Specific inhibition by 11α-hydroxyprogesterone

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The 11β-hydroxysteroid dehydrogenase type 2 (11βHSD-2) enzyme is thought to confer aldosterone specificity upon mineralocorticoid target tissues by protecting the mineralocorticoid receptor from binding by the more abundant glucocorticoids, corticosterone and cortisol. We have developed a Chinese ha...

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Detalles Bibliográficos
Autores principales:	Morita, H., Zhou, M., Foecking, M.F., Gomez-Sanchez, E.P., Cozza, E.N., Gomez-Sanchez, C.E.
Formato:	JOUR
Materias:	11alpha hydroxyprogesterone 11beta hydroxysteroid dehydrogenase animal cell article Chinese hamster competitive inhibition enzyme activity enzyme inhibition enzyme kinetics genetic complementation genetic transfection glycosylation nonhuman potassium excretion priority journal sodium retention
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00137227_v137_n6_p2308_Morita
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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