Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats
The effect of pinealectomy (Px) on the development of steroid positive feedback on luteinizing hormone (LH) release was examined in female rats subjected to surgery at 10 days of age. Estradiol-progesterone injection decreased serum LH in sham Px or intact controls younger than 20 days, while a sign...
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| Formato: | JOUR |
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| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00068993_v241_n2_p366_Faigon |
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todo:paper_00068993_v241_n2_p366_Faigon2023-10-03T14:05:20Z Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats Faigón, M.R. Cardinali, D.P. Moguilevsky, J.A. luteinizing hormone release melatonin pineal gland puberty estradiol gonadorelin luteinizing hormone melatonin progesterone animal experiment central nervous system endocrine system feedback system pineal body pinealectomy puberty rat subcutaneous drug administration Animal Estradiol Feedback Female Luteinizing Hormone Pineal Gland Progesterone Rats Rats, Inbred Strains Sex Maturation Support, Non-U.S. Gov't The effect of pinealectomy (Px) on the development of steroid positive feedback on luteinizing hormone (LH) release was examined in female rats subjected to surgery at 10 days of age. Estradiol-progesterone injection decreased serum LH in sham Px or intact controls younger than 20 days, while a significant LH release was found at day 22; Px rats showed a steroid-induced LH depression only at day 16, a positive feedback being detectable at day 20, 2 days earlier than in sham Px or intact rats. Daily injections of 10-50 μg melatonin to intact rats disrupted the LH negative feedback response at day 20, and diminished steroid-induced LH release at day 24. © 1982. JOUR info:eu-repo/semantics/openAccess http://creativecommons.org/licenses/by/2.5/ar http://hdl.handle.net/20.500.12110/paper_00068993_v241_n2_p366_Faigon |
| institution |
Universidad de Buenos Aires |
| institution_str |
I-28 |
| repository_str |
R-134 |
| collection |
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) |
| topic |
luteinizing hormone release melatonin pineal gland puberty estradiol gonadorelin luteinizing hormone melatonin progesterone animal experiment central nervous system endocrine system feedback system pineal body pinealectomy puberty rat subcutaneous drug administration Animal Estradiol Feedback Female Luteinizing Hormone Pineal Gland Progesterone Rats Rats, Inbred Strains Sex Maturation Support, Non-U.S. Gov't |
| spellingShingle |
luteinizing hormone release melatonin pineal gland puberty estradiol gonadorelin luteinizing hormone melatonin progesterone animal experiment central nervous system endocrine system feedback system pineal body pinealectomy puberty rat subcutaneous drug administration Animal Estradiol Feedback Female Luteinizing Hormone Pineal Gland Progesterone Rats Rats, Inbred Strains Sex Maturation Support, Non-U.S. Gov't Faigón, M.R. Cardinali, D.P. Moguilevsky, J.A. Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats |
| topic_facet |
luteinizing hormone release melatonin pineal gland puberty estradiol gonadorelin luteinizing hormone melatonin progesterone animal experiment central nervous system endocrine system feedback system pineal body pinealectomy puberty rat subcutaneous drug administration Animal Estradiol Feedback Female Luteinizing Hormone Pineal Gland Progesterone Rats Rats, Inbred Strains Sex Maturation Support, Non-U.S. Gov't |
| description |
The effect of pinealectomy (Px) on the development of steroid positive feedback on luteinizing hormone (LH) release was examined in female rats subjected to surgery at 10 days of age. Estradiol-progesterone injection decreased serum LH in sham Px or intact controls younger than 20 days, while a significant LH release was found at day 22; Px rats showed a steroid-induced LH depression only at day 16, a positive feedback being detectable at day 20, 2 days earlier than in sham Px or intact rats. Daily injections of 10-50 μg melatonin to intact rats disrupted the LH negative feedback response at day 20, and diminished steroid-induced LH release at day 24. © 1982. |
| format |
JOUR |
| author |
Faigón, M.R. Cardinali, D.P. Moguilevsky, J.A. |
| author_facet |
Faigón, M.R. Cardinali, D.P. Moguilevsky, J.A. |
| author_sort |
Faigón, M.R. |
| title |
Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats |
| title_short |
Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats |
| title_full |
Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats |
| title_fullStr |
Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats |
| title_full_unstemmed |
Pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats |
| title_sort |
pinealectomy advances the time of development of steroid feedback on luteinizing hormone release in immature female rats |
| url |
http://hdl.handle.net/20.500.12110/paper_00068993_v241_n2_p366_Faigon |
| work_keys_str_mv |
AT faigonmr pinealectomyadvancesthetimeofdevelopmentofsteroidfeedbackonluteinizinghormonereleaseinimmaturefemalerats AT cardinalidp pinealectomyadvancesthetimeofdevelopmentofsteroidfeedbackonluteinizinghormonereleaseinimmaturefemalerats AT moguilevskyja pinealectomyadvancesthetimeofdevelopmentofsteroidfeedbackonluteinizinghormonereleaseinimmaturefemalerats |
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