Neuronal and astroglial alterations in the hippocampus of a mouse model for type 1 diabetes

The influence of diabetes mellitus on brain pathology is increasingly recognized. Previous contributions of our laboratory demonstrated in models of type 1 diabetes (nonobese diabetic and streptozotocin (STZ)-treated mice), a marked astrogliosis and neurogenesis deficit in hippocampus and increased...

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Detalles Bibliográficos
Autores principales: Revsin, Y., Saravia, F., Roig, P., Lima, A., De Kloet, E.R., Homo-Delarche, F., De Nicola, A.F.
Formato: JOUR
Materias:
Apolipoprotein-E, Fos, Jun, NADPH-diaphorase
Astrocytes
Diabetes mellitus
Hippocampus
Neurodegeneration
Neurons
Streptozotocin
apolipoprotein E
gene product
molecular marker
protein c fos
protein c jun
reduced nicotinamide adenine dinucleotide phosphate dehydrogenase
streptozocin
animal experiment
animal model
animal tissue
article
brain cortex
brain region
cell activation
cell count
controlled study
dentate gyrus
enzyme activity
female
gene expression
gene mutation
genetic analysis
genetic linkage
hippocampus
insulin dependent diabetes mellitus
macroglia
mouse
nerve cell lesion
nonhuman
oxidative stress
priority journal
streptozocin diabetes
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00068993_v1038_n1_p22_Revsin
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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