Intrabursal administration of the antiangiopoietin 1 antibody produces a delay in rat follicular development associated with an increase in ovarian apoptosis mediated by changes in the expression of BCL2 related genes

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The angiopoietin (ANGPT) receptor (TEK) system plays a crucial role in blood vessel development and regression. To date, no reports have addressed the actions of the anti-ANGPT1 antibody on gonadotropin-stimulated follicular development and atresia in the ovary. Therefore, in this study we specifica...

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Detalles Bibliográficos
Autores principales: Parborell, F., Abramovich, D., Tesone, M.
Formato: JOUR
Materias:
Angiogenesis
Angiopoietin 1
Apoptosis
Follicle
Ovary
angiopoietin 1
angiopoietin 1 antibody
Fas antigen
Fas ligand
gonadotropin
inhibitor of apoptosis protein
protein antibody
protein Bax
protein bcl 2
protein bcl x
unclassified drug
angiogenesis
animal cell
animal experiment
animal model
apoptosis
article
cell culture
controlled study
culture medium
DNA fragmentation
gene expression
granulosa cell
nonhuman
ovary
ovary follicle
ovary follicle atresia
ovary follicle development
paracrine signaling
prepuberty
priority journal
protein blood level
protein expression
protein family
protein function
rat
theca cell
Angiopoietin-1
Animals
Antibodies
Cell Count
DNA Fragmentation
Endothelium
Female
Gene Expression Regulation, Developmental
Gonadotropins
Injections, Intraperitoneal
Ovarian Follicle
Peritoneal Cavity
Proto-Oncogene Proteins c-bcl-2
Rats
Rats, Sprague-Dawley
Sexual Maturation
Rattus
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00063363_v78_n3_p506_Parborell
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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