Gonadotropin-releasing hormone antagonist antide inhibits apoptosis of preovulatory follicle cells in rat ovary

Analogs of GnRH, including agonists (GnRH-a) and antagonists (GnRH-ant), have been widely used to inhibit gonadotropin pituitary release. Aside from the effect of GnRH analogs on the pituitary-gonadal axis, studies have shown that GnRH has extrapituitary effects, particularly on rat and human ovarie...

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Detalles Bibliográficos
Autores principales: Parborell, F., Irusta, G., Vitale, A., Gonzalez, O., Pecci, A., Tesone, M.
Formato: JOUR
Materias:
Apoptosis
Follicle
Gonadotropin-releasing hormone
Ovary
4 (2 hydroxyethyl) 1 piperazineethanesulfonic acid
cytochrome c
diethylstilbestrol
gonadorelin agonist
gonadorelin antagonist
iturelix
leuprorelin
protein Bax
protein bcl 2
agonist
animal cell
animal experiment
apoptosis
article
cell count
comparative study
controlled study
cytosol
drug effect
drug inhibition
female
gonadotropin release
hormone inhibition
mitochondrial membrane
nonhuman
organ weight
ovary follicle
ovary follicle atresia
ovary follicle maturation
ovary weight
prepuberty
priority journal
protein family
protein synthesis inhibition
rat
species comparison
Animals
bcl-2-Associated X Protein
Cytochromes c
Estrous Cycle
Female
Gonadotropin-Releasing Hormone
Hormone Antagonists
Leuprolide
Oligopeptides
Ovarian Follicle
Proto-Oncogene Proteins c-bcl-2
Rats
Rats, Sprague-Dawley
Animalia
Formicidae
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00063363_v72_n3_p659_Parborell
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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