Modification of sarcolemmal enzymes by chagasic IgG and its effect of cardiac contractility
It has been shown that sera from chagasic patients contain an antibody which binds to β-adrenoceptors of myocardium and modulates their activity. Chagasic IgG triggered a marked stimulation of myocardial contractility with an increase in intramyocardial cyclic AMP and inhibition of (Na+ + K+)-ATPase...
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| Autores principales: | , , , , |
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| Formato: | JOUR |
| Materias: | |
| Acceso en línea: | http://hdl.handle.net/20.500.12110/paper_00062952_v35_n21_p3839_Pascual |
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