Defective 30S ribosomal particles in a polyamine auxotroph of Escherichia coli

Polypeptide synthesis directed by poly(U) or MS 2 phage RNA is several fold more active in cell-free systems prepared from polyamine supplemented bacteria than in extracts of polyamine depleted cells. This effect depends on the presence of defective 30S ribosomal subunits in the starved bacteria. It...

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Detalles Bibliográficos
Autores principales: Echandi, G., Algranati, I.D.
Formato: JOUR
Materias:
polyamine
putrescine
auxotrophic mutant
escherichia coli
in vitro study
microorganism
protein synthesis
ribosome
theoretical study
Escherichia coli
Kinetics
Magnesium
Peptide Synthesis
Poly U
Polyamines
Putrescine
Ribosomes
RNA, Viral
Spermidine
Translation, Genetic
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_0006291X_v67_n3_p1185_Echandi
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:Polypeptide synthesis directed by poly(U) or MS 2 phage RNA is several fold more active in cell-free systems prepared from polyamine supplemented bacteria than in extracts of polyamine depleted cells. This effect depends on the presence of defective 30S ribosomal subunits in the starved bacteria. It is concluded that polyamines play a role in the normal biosynthesis, maturation and/or assembly of the small ribosomal subparticles. © 1975.

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