In vitro effect of a new cinnamic acid derivative against the epimastigote form of Trypanosoma cruzi

An intensive effort has been directed toward finding alternative drugs for treatment of Chagas' disease, caused by Trypanosoma cruzi (T. cruzi), and prophylaxis of blood in endemic areas. The preparation and in vitro evaluation as potential anti-protozoal agent of (2E)-N-(1,3-benzothiazol-2-yl)...

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Detalles Bibliográficos
Autores principales:	Andreu, G.L.P., Inada, N.M., Pellón, R.F., Docampo, M.L., Fascio, M.L., D'Accorso, N.B., Vercesi, A.E.
Formato:	JOUR
Materias:	Anti-protozoal agents Chagas' disease Cinnamic acid Epimastigotes Mitochondria Oxidative stress Trypanosoma cruzi cad 1 cinnamic acid derivative n (1,3 benzothiazol 2 yl) 3 (2,5 dimethoxyphenyl) 2 propenamide reactive oxygen metabolite unclassified drug antiprotozoal activity article drug mechanism drug structure epimastigote in vitro study mitochondrial membrane potential nonhuman Amides Animals Annexin A5 Benzothiazoles Cinnamates Coloring Agents Enzyme Inhibitors Flow Cytometry Indicators and Reagents Membrane Potentials Propidium Reactive Oxygen Species Trypanocidal Agents
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00044172_v59_n4_p207_Andreu
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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