E2F1-mediated upregulation of p19INK4d determines its periodic expression during cell cycle and regulates cellular proliferation

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Background: A central aspect of development and disease is the control of cell proliferation through regulation of the mitotic cycle. Cell cycle progression and directionality requires an appropriate balance of positive and negative regulators whose expression must fluctuate in a coordinated manner....

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Detalles Bibliográficos
Autores principales: Carcagno, A.L., Marazita, M.C., Ogara, M.F., Ceruti, J.M., Sonzogni, S.V., Scassa, M.E., Giono, L.E., Cánepa, E.T.
Formato: Artículo publishedVersion
Lenguaje:Inglés
Publicado: 2011
Materias:
cyclin dependent kinase inhibitor 2D
cyclin E
transcription factor E2F1
CCNE1 protein, human
CDKN2D protein, human
oncoprotein
animal cell
article
cell cycle progression
cell cycle S phase
cell proliferation
controlled study
embryo
human
human cell
nonhuman
promoter region
protein expression
transcription regulation
upregulation
animal
binding site
biological model
cell cycle
cell line
feedback system
genetic transcription
genetics
metabolism
molecular genetics
nucleotide sequence
periodicity
protein binding
Animals
Base Sequence
Binding Sites
Cell Cycle
Cell Line
Cell Proliferation
Conserved Sequence
Cyclin E
Cyclin-Dependent Kinase Inhibitor p19
E2F1 Transcription Factor
Feedback, Physiological
Humans
Models, Biological
Molecular Sequence Data
Oncogene Proteins
Periodicity
Promoter Regions, Genetic
Protein Binding
Transcription, Genetic
Up-Regulation
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_19326203_v6_n7_p_Carcagno
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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