Mouse mammary tumors display Stat3 activation dependent on leukemia inhibitory factor signaling

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Introduction: It has been demonstrated that leukemia inhibitory factor (LIF) induces epithelium apoptosis through Stat3 activation during mouse mammary gland involution. In contrast, it has been shown that this transcription factor is commonly activated in breast cancer cells, although what causes t...

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Autores principales:	Quaglino, A., Schere-Levy, C., Romorini, L., Meiss, R.P., Kordon, E.C.
Formato:	Artículo publishedVersion
Lenguaje:	Inglés
Publicado:	2007
Materias:	2 (2 amino 3 methoxyphenyl)chromone crystal violet leukemia inhibitory factor mitogen activated protein kinase 1 mitogen activated protein kinase 3 protein antibody STAT3 protein leukemia inhibitory factor receptor alpha Lif protein, mouse Lifr protein, mouse messenger RNA Stat3 protein, mouse tyrosine unclassified drug animal cell animal experiment animal model article breast tumor cell survival female human human cell immunohistochemistry mouse nonhuman phosphorylation protein analysis protein expression protein function reverse transcription polymerase chain reaction Western blotting animal Bagg albino mouse cell culture experimental neoplasm fluorescent antibody technique genetics immunoprecipitation metabolism pathology signal transduction Animals Blotting, Western Cell Survival Female Fluorescent Antibody Technique Immunoprecipitation Leukemia Inhibitory Factor Leukemia Inhibitory Factor Receptor alpha Subunit Mammary Neoplasms, Experimental Mice Mice, Inbred BALB C Mitogen-Activated Protein Kinase 1 Mitogen-Activated Protein Kinase 3 Phosphorylation Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger Signal Transduction STAT3 Transcription Factor Tumor Cells, Cultured Tyrosine
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_14655411_v9_n5_p_Quaglino
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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