Elimination of D-lactate synthesis increases poly(3-hydroxybutyrate) and ethanol synthesis from glycerol and affects cofactor distribution in recombinant Escherichia coli

Mostrar todas las versiones(3)

The effect of eliminating D-lactate synthesis in poly(3-hydroxybutyrate) (PHB)-accumulating recombinant Escherichia coli (K24K) was analyzed using glycerol as a substrate. K24KL, an ldhA derivative, produced more biomass and had altered carbon partitioning among the metabolic products, probably due...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Nikel, P.I., Giordano, A.M., De Almeida, A., Godoy, M.S., Pettinari, M.J.
Formato: Artículo publishedVersion
Lenguaje:Inglés
Publicado: 2010
Materias:
Carbon partitioning
Carbon precursors
Cofactors
D-lactate
Fed-batch cultures
Metabolic products
Poly(3-hydroxybutyrate)
Recombinant Escherichia coli
Reducing power
Batch cell culture
Escherichia coli
Ethanol
Substrates
Glycerol
alcohol
carbon
glycerol
hydroxybutyric acid
lactate dehydrogenase
lactic acid
nicotinamide adenine dinucleotide
nicotinamide adenine dinucleotide phosphate
poly(3 hydroxybutyric acid)
poly-beta-hydroxybutyrate
polyester
biomass
ester
ethanol
fecal coliform
partitioning
recombination
article
bioreactor
chemistry
genetics
growth, development and aging
metabolism
time
Biomass
Bioreactors
Carbon
Hydroxybutyrates
Lactate Dehydrogenases
Lactic Acid
Metabolic Networks and Pathways
NAD
NADP
Polyesters
Time Factors
Acceso en línea:http://hdl.handle.net/20.500.12110/paper_00992240_v76_n22_p7400_Nikel
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Ejemplares similares