Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma

Mostrar todas las versiones(3)

Kaposi's sarcoma (KS), a multifocal vascular neoplasm linked to human herpesvirus-8 (HHV-8/KS-associated herpesvirus [KSHV]) infection, is the most common AIDS-associated malignancy. Clinical management of KS has proven to be challenging because of its prevalence in immunosuppressed patients an...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Croci, D.O., Salatino, M., Rubinstein, N., Cerliani, J.P., Cavallin, L.E., Leung, H.J., Ouyang, J., Ilarregui, J.M., Toscano, M.A., Domaica, C.I., Croci, M.C., Shipp, M.A., Mesri, E.A., Albini, A., Rabinovich, G.A.
Formato:	Artículo publishedVersion
Lenguaje:	Inglés
Publicado:	2012
Materias:	galectin 1 glycan hypoxia inducible factor 1alpha hypoxia inducible factor 2alpha immunoglobulin enhancer binding protein messenger RNA monoclonal antibody reactive oxygen metabolite angiogenesis animal cell animal experiment animal model animal tissue apoptosis article carcinogenesis cell growth cell invasion cell migration cell proliferation controlled study human human cell human tissue hypoxia in vivo study Kaposi sarcoma male mouse nonhuman priority journal protein expression protein function protein protein interaction protein targeting spindle cell tumor regression Animals Anoxia Antibodies, Monoclonal Antibodies, Neutralizing Cell Hypoxia Cell Line, Tumor Cells, Cultured Galectin 1 Gene Expression Regulation, Neoplastic HEK293 Cells Herpesvirus 8, Human Host-Pathogen Interactions Humans Immunoblotting Mice Mice, Inbred C57BL Mice, Knockout Mice, Nude Neovascularization, Pathologic Polysaccharides Protein Binding Reverse Transcriptase Polymerase Chain Reaction RNA Interference Sarcoma, Kaposi Xenograft Model Antitumor Assays
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00221007_v209_n11_p1985_Croci
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma
por: Croci, D.O., et al.
Publicado: (2012)

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma
por: Croci, D.O., et al.

Disrupting galectin-1 interactions with N-glycans suppresses hypoxia-driven angiogenesis and tumorigenesis in Kaposi's sarcoma
por: Croci Russo, Diego Omar, et al.
Publicado: (2012)

RSUME is implicated in HIF-1-induced VEGF-A production in pituitary tumour cells
por: Shan, B., et al.

RSUME is implicated in HIF-1-induced VEGF-A production in pituitary tumour cells
Publicado: (2012)

RSUME, a Small RWD-Containing Protein, Enhances SUMO Conjugation and Stabilizes HIF-1α during Hypoxia
por: Carbia-Nagashima, A., et al.
Publicado: (2007)

RSUME, a Small RWD-Containing Protein, Enhances SUMO Conjugation and Stabilizes HIF-1α during Hypoxia
por: Carbia-Nagashima, A., et al.
Publicado: (2007)

RSUME, a Small RWD-Containing Protein, Enhances SUMO Conjugation and Stabilizes HIF-1α during Hypoxia
por: Carbia-Nagashima, A., et al.

RSUME, a Small RWD-Containing Protein, Enhances SUMO Conjugation and Stabilizes HIF-1α during Hypoxia
por: Carbia Nagashima, Alberto Nicolás, et al.
Publicado: (2007)

Modulation of the Akt Pathway Reveals a Novel Link with PERK/eIF2α, which Is Relevant during Hypoxia
por: Blaustein, M., et al.
Publicado: (2013)

Modulation of the Akt Pathway Reveals a Novel Link with PERK/eIF2α, which Is Relevant during Hypoxia
por: Blaustein, M., et al.
Publicado: (2013)

Modulation of the Akt Pathway Reveals a Novel Link with PERK/eIF2α, which Is Relevant during Hypoxia
por: Blaustein, M., et al.

Curcumin suppresses HIF1A synthesis and VEGFA release in pituitary adenomas
por: Shan, B., et al.

Musashi mediates translational repression of the Drosophila hypoxia inducible factor
por: Bertolin, A.P., et al.

Galectins: emerging regulatory checkpoints linking tumor immunity and angiogenesis
por: Méndez-Huergo, S.P., et al.

Glycosylation-dependent galectin–receptor interactions promote Chlamydia trachomatis infection
por: Lujan, A.L., et al.

Curcumin suppresses HIF1A synthesis and VEGFA release in pituitary adenomas
Publicado: (2012)

Modulation of the Akt Pathway Reveals a Novel Link with PERK/eIF2α, which Is Relevant during Hypoxia
por: Blaustein Kappelmacher, Matias, et al.
Publicado: (2013)

Galectins: emerging regulatory checkpoints linking tumor immunity and angiogenesis
Publicado: (2017)

RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors
por: Wu, Y., et al.

Musashi mediates translational repression of the Drosophila hypoxia inducible factor
por: Pozzi, Maria Berta, et al.
Publicado: (2016)

Dissecting the signal transduction pathways triggered by galectin-glycan interactions in physiological and pathological settings
por: Laderach, D.J., et al.
Publicado: (2010)

Dissecting the signal transduction pathways triggered by galectin-glycan interactions in physiological and pathological settings
por: Laderach, D.J., et al.
Publicado: (2010)

Dissecting the signal transduction pathways triggered by galectin-glycan interactions in physiological and pathological settings
por: Laderach, D.J., et al.

Glycosylation-dependent galectin–receptor interactions promote Chlamydia trachomatis infection
Publicado: (2018)

RSUME is implicated in tumorigenesis and metastasis of pancreatic neuroendocrine tumors
Publicado: (2016)

Modulation of endothelial cell migration and angiogenesis: A novel function for the "tandem-repeat" lectin galectin-8
por: Cárdenas Delgado, V.M., et al.

Modulation of endothelial cell migration and angiogenesis: A novel function for the "tandem-repeat" lectin galectin-8
por: Troncoso, María Fernanda, et al.
Publicado: (2011)

Dissecting the signal transduction pathways triggered by galectin-glycan interactions in physiological and pathological settings
por: Toscano, Marta Alicia, et al.
Publicado: (2010)

Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptors
por: Bae, G.-U., et al.

Glycosylation-dependent lectin-receptor interactions preserve angiogenesis in anti-VEGF refractory tumors
por: Croci, D.O., et al.

The glycan-binding protein galectin-1 controls survival of epithelial cells along the crypt-villus axis of small intestine
por: Muglia, C., et al.

Endocannabinoids participate in placental apoptosis induced by hypoxia inducible factor-1
por: Abán, C., et al.

Mutations in CDON, encoding a hedgehog receptor, result in holoprosencephaly and defective interactions with other hedgehog receptors
Publicado: (2011)

The Gα12/13 family of heterotrimeric G proteins and the small GTPase RhoA link the Kaposi sarcoma-associated herpes virus G protein-coupled receptor to heme oxygenase-1 expression and tumorigenesis
por: Martín, M.J., et al.
Publicado: (2007)

The Gα12/13 family of heterotrimeric G proteins and the small GTPase RhoA link the Kaposi sarcoma-associated herpes virus G protein-coupled receptor to heme oxygenase-1 expression and tumorigenesis
por: Martín, M.J., et al.
Publicado: (2007)

The Gα12/13 family of heterotrimeric G proteins and the small GTPase RhoA link the Kaposi sarcoma-associated herpes virus G protein-coupled receptor to heme oxygenase-1 expression and tumorigenesis
por: Martín, M.J., et al.

miR-190 Enhances HIF-Dependent Responses to Hypoxia in Drosophila by Inhibiting the Prolyl-4-hydroxylase Fatiga
por: De Lella Ezcurra, A.L., et al.

Glycobiology of cell death: When glycans and lectins govern cell fate
por: Lichtenstein, R.G., et al.

Central role of the oxygen-dependent degradation domain of Drosophila HIFα/Sima in oxygen-dependent nuclear export
por: Irisarri, M., et al.