Localization of vascular endothelial growth factor (VEGF) receptors in normal and adenomatous pituitaries: Detection of a non-endothelial function of VEGF in pituitary tumours

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As for any solid tumour, pituitary adenoma expansion is dependent on neovascularization through angiogenesis. In this process, vascular endothelial growth factor (VEGF) and its receptors VEGFR-1, VEGFR-2 and neuropilin-1 (NRP-1) may play an outstanding role. The intention of this work was to study t...

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Detalles Bibliográficos
Autores principales:	Onofri, C., Theodoropoulou, M., Losa, M., Uhl, E., Lange, M., Arzt, E., Stalla, G.K., Renner, U.
Formato:	Artículo publishedVersion
Lenguaje:	Inglés
Publicado:	2006
Materias:	cyclin D1 messenger RNA neuropilin 1 phosphatidylinositol 3 kinase placental growth factor protein bcl 2 vasculotropin A vasculotropin receptor vasculotropin receptor 1 vasculotropin receptor 2 adult aged animal cell article cell proliferation controlled study endocrine cell endothelium cell epithelium tumor female gene expression human human cell human tissue hypophysis adenoma immunohistochemistry in situ hybridization male nonhuman nucleotide sequence priority journal protein expression protein function protein localization rat real time polymerase chain reaction tumor growth tumor vascularization 1-Phosphatidylinositol 3-Kinase Adenoma Adult Aged Animals Antibodies, Monoclonal Blotting, Western Cell Line, Tumor Cell Proliferation Chromones Endothelial Cells Female Humans Immunohistochemistry In Situ Hybridization Ligands Male Middle Aged Morpholines Neuropilin-1 Pituitary Gland Pituitary Neoplasms Rats Receptors, Vascular Endothelial Growth Factor Reverse Transcriptase Polymerase Chain Reaction Somatotrophs Stimulation, Chemical Vascular Endothelial Growth Factor A Vascular Endothelial Growth Factor Receptor-1 Vascular Endothelial Growth Factor Receptor-2
Acceso en línea:	http://hdl.handle.net/20.500.12110/paper_00220795_v191_n1_p249_Onofri
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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