Melatonin modulates drug-induced acute porphyria

This work investigated the modulation by melatonin (Mel) of the effects of the porphyrinogenic drugs 2-allyl-2-isopropylacetamide (AIA) and 3,5-diethoxycarbonyl-1,4-dihydro-2,4,6-collidine (DDC) on oxidative environment, glucose biosynthesis and heme pathway parameters. Administration of Mel before...

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Detalles Bibliográficos
Autores principales:	Mazzetti, Marta Blanca, San Martín de Viale, Leonor Carmen
Publicado:	2016
Materias:	Acute porphyria Glucose synthesis Heme pathway Melatonin Oxidative stress 1,4 dihydro 2,4,6 trimethyl 3,5 pyridinedicarboxylic acid diethyl ester allylisopropylacetamide aminolevulinic acid ferrochelatase glucose glucose 6 phosphatase heme melatonin phosphoenolpyruvate carboxykinase (GTP) reactive oxygen metabolite thiobarbituric acid reactive substance acute intermittent porphyria animal model animal tissue Article controlled study enzyme activity female gluconeogenesis glucose metabolism intoxication lipid peroxidation microsome nonhuman oxidative stress protein analysis rat
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_22147500_v3_n_p141_Lelli http://hdl.handle.net/20.500.12110/paper_22147500_v3_n_p141_Lelli
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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