Delineating the "galectin signature" of the tumor microenvironment

Galectins, a family of glycan-binding proteins, can control tumor progression by promoting transformation, angiogenesis and immune escape. We identified a dynamically regulated 'galectin signature', which delineates the progression of prostate cancer, highlighting galectin-1 as an attracti...

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Detalles Bibliográficos
Publicado: 2013
Materias:
Angiogenesis
Galectins
Gene signature
Metastasis
Prostate cancer
angiogenesis inhibitor
ecalectin
galectin
galectin 1
galectin 12
galectin 3
galectin 4
galectin 8
messenger RNA
short hairpin RNA
unclassified drug
advanced cancer
antiangiogenic therapy
article
cancer cell culture
cancer growth
cancer prognosis
cancer staging
cancer therapy
castration resistant prostate cancer
cell invasion
cell migration
cellular immunity
down regulation
human
hypoxia
Kaposi sarcoma
molecular mechanics
prostate cancer
prostatectomy
protein carbohydrate interaction
protein expression
protein function
protein structure
protein synthesis inhibition
protein targeting
structure analysis
tumor microenvironment
tumor vascularization
upregulation
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_21624011_v2_n4_p_Compagno
http://hdl.handle.net/20.500.12110/paper_21624011_v2_n4_p_Compagno
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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