Role of the ERK1/2 signaling pathway in the replication of junín and tacaribe viruses

We have previously shown that the infection of cell cultures with the arenaviruses Junín (JUNV), Tacaribe (TCRV), and Pichindé promotes the phosphorylation of mitogen-activated protein kinases (MAPKs) extracellular signal-regulated kinases 1 and 2 (ERK1/2) and that this activation is required for th...

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Guardado en:
Detalles Bibliográficos
Publicado: 2018
Materias:
Arenavirus
Cell signaling
ERK
Junín virus
Replication
Tacaribe virus
1,4 diamino 1,4 bis(2 aminophenylthio) 2,3 dicyanobutadiene
chlorpromazine
messenger RNA
mitogen activated protein kinase 1
mitogen activated protein kinase 3
ribavirin
small interfering RNA
viral protein
1,3 butadiene
enzyme inhibitor
nitrile
virus RNA
animal cell
Article
cell proliferation
cell viability
controlled study
gene expression
genetic transfection
immunofluorescence test
Junin virus
nonhuman
phosphorylation
protein expression
real time polymerase chain reaction
reverse transcription polymerase chain reaction
signal transduction
virus entry
virus infectivity
virus replication
Western blotting
animal
biosynthesis
cell line
host pathogen interaction
MAPK signaling
metabolism
New World arenavirus
physiology
Animals
Arenaviruses, New World
Butadienes
Cell Line
Enzyme Inhibitors
Host-Pathogen Interactions
MAP Kinase Signaling System
Nitriles
RNA, Viral
Viral Proteins
Virus Replication
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_19994915_v10_n4_p_Brunetti
http://hdl.handle.net/20.500.12110/paper_19994915_v10_n4_p_Brunetti
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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