Blockade of dengue virus entry into myeloid cells by endocytic inhibitors in the presence or absence of antibodies

Background: Dengue is the most prevalent arthropod-borne viral human disease in tropical and subtropical regions, caused by four dengue virus (DENV) serotypes. In spite of the increasing global incidence, no specific antiviral therapy is available. Cells of the mononuclear phagocyte lineage are the...

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Guardado en:
Detalles Bibliográficos
Publicado: 2018
Materias:
acridine orange
ammonium chloride
antivirus agent
CD32 antigen
chlorpromazine
cholera toxin B subunit
clathrin
dansylcadaverine
dengue virus monoclonal antibody 2h2
dengue virus monoclonal antibody 3h5
dynamin
dynasore
E2 protein
Fc receptor
fluorescein isothiocyanate
methyl beta cyclodextrin
monoclonal antibody
unclassified drug
viral protein
virus antibody
virus RNA
beta cyclodextrin derivative
hydrazone derivative
methyl-beta-cyclodextrin
N'-(3,4-dihydroxybenzylidene)-3-hydroxy-2-naphthahydrazide
animal cell
antigen antibody complex
Article
bone marrow cell
C6/36 cell line
cell viability
clathrin-coated vesicle
controlled study
Dengue virus 2
endocytosis
endosome
fluorescence microscopy
human
human cell
infection
K-562 cell line
nonhuman
pH
quantitative analysis
real time polymerase chain reaction
reverse transcription polymerase chain reaction
serotype
U-937 cell line
Vero cell line
viral plaque assay
virion
virus entry
virus infectivity
virus load
cell survival
Dengue virus
drug effect
physiology
virology
Ammonium Chloride
Antibodies, Viral
beta-Cyclodextrins
Cell Survival
Chlorpromazine
Dengue Virus
Endocytosis
Humans
Hydrazones
K562 Cells
Myeloid Cells
U937 Cells
Virus Internalization
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_19352727_v12_n8_p_Carro
http://hdl.handle.net/20.500.12110/paper_19352727_v12_n8_p_Carro
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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