Human Natural Killer Cell Maturation Defect Supports In Vivo CD56bright to CD56dim Lineage Development

Two populations of human natural killer (NK) cells can be identified in peripheral blood. The majority are CD3-CD56dim cells while the minority exhibits a CD3-CD56bright phenotype. In vitro evidence indicates that CD56bright cells are precursors of CD56dim cells, but in vivo evidence is lacking. Her...

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Detalles Bibliográficos
Autores principales: Domaica, Carolina Inés, Fuertes, Mercedes Beatriz, Girart, María Victoria
Publicado: 2012
Materias:
CD158 antigen
CD16 antigen
CD3 antigen
CD56 antigen
CD57 antigen
CD94 antigen
cell antigen
cell protein
gamma interferon
natural cytotoxicity triggering receptor 1
natural killer cell receptor NKG2A
natural killer cell receptor NKG2D
perforin
protein 2B4
protein DNAM 1
unclassified drug
adolescent
antigen expression
article
cell lineage
cell maturation
controlled study
cytokine response
down regulation
human
human cell
in vivo study
lymphocyte activation
lymphocyte differentiation
lymphocyte migration
lymphocyte subpopulation
melanoma
natural killer cell
opportunistic infection
phenotypic variation
protein expression
upregulation
Antigens, CD56
Cell Differentiation
Cell Lineage
Flow Cytometry
Humans
Interferon-gamma
K562 Cells
Killer Cells, Natural
Leukocytes, Mononuclear
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_19326203_v7_n12_p_Domaica
http://hdl.handle.net/20.500.12110/paper_19326203_v7_n12_p_Domaica
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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