The smoking gun in nicotine-induced anorexia

Hypothalamic pro-opiomelanocortin (POMC) neurons are the major source of anorectic melanocortin peptides in the brain. A recent study (Mineur et al., 2011) demonstrates that nicotine directly stimulates arcuate POMC neurons through nicotinic acetylcholinergic α3β4 receptors, suggesting a new mechani...

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Detalles Bibliográficos
Autor principal: Rubinstein, Marcelo
Publicado: 2011
Materias:
acetylcholine
anorexigenic agent
nicotine
nicotinic receptor
nicotinic receptor alpha3beta4
proopiomelanocortin
unclassified drug
varenicline
anorexia
anxiety
body weight
caloric intake
cigarette smoking
food intake
human
hypothalamus
nerve cell
nonhuman
priority journal
short survey
smoking
smoking cessation
Nicotiana tabacum
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15504131_v14_n2_p145_Rubinstein
http://hdl.handle.net/20.500.12110/paper_15504131_v14_n2_p145_Rubinstein
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:Hypothalamic pro-opiomelanocortin (POMC) neurons are the major source of anorectic melanocortin peptides in the brain. A recent study (Mineur et al., 2011) demonstrates that nicotine directly stimulates arcuate POMC neurons through nicotinic acetylcholinergic α3β4 receptors, suggesting a new mechanism to understand the inverse relationship between tobacco smoking and body weight. © 2011 Elsevier Inc.

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