A bumpy road for RNA polymerase II

The identification of a second regulatory checkpoint controlling RNA polymerase II elongation near the poly(A) site of protein-coding genes reveals an additional level of complexity in the modulation of eukaryotic transcriptional elongation and termination. © 2015 Nature America, Inc. All rights res...

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Autores principales:	Giono, Luciana Eugenia, Kornblihtt, Alberto Rodolfo
Publicado:	2015
Materias:	cyclin dependent kinase 9 histone messenger RNA precursor polyadenylic acid RNA polymerase II glyceraldehyde 3 phosphate dehydrogenase Article chromatin structure enzyme activity enzyme inhibition eukaryote histone modification nucleosome polyadenylation priority journal promoter region protein cleavage protein DNA interaction protein function RNA processing signal transduction transcription elongation transcription initiation site transcription regulation transcription termination antagonists and inhibitors biosynthesis drug effects genetic transcription human RNA translation Eukaryota Cyclin-Dependent Kinase 9 Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) Humans Peptide Chain Elongation, Translational Transcription, Genetic
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15459993_v22_n5_p353_Giono http://hdl.handle.net/20.500.12110/paper_15459993_v22_n5_p353_Giono
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_15459993_v22_n5_p353_Giono
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spelling	paper:paper_15459993_v22_n5_p353_Giono2023-06-08T16:21:15Z A bumpy road for RNA polymerase II Giono, Luciana Eugenia Kornblihtt, Alberto Rodolfo cyclin dependent kinase 9 histone messenger RNA precursor polyadenylic acid RNA polymerase II cyclin dependent kinase 9 glyceraldehyde 3 phosphate dehydrogenase Article chromatin structure enzyme activity enzyme inhibition eukaryote histone modification nucleosome polyadenylation priority journal promoter region protein cleavage protein DNA interaction protein function RNA processing signal transduction transcription elongation transcription initiation site transcription regulation transcription termination antagonists and inhibitors biosynthesis drug effects genetic transcription human RNA translation Eukaryota Cyclin-Dependent Kinase 9 Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) Humans Peptide Chain Elongation, Translational Transcription, Genetic The identification of a second regulatory checkpoint controlling RNA polymerase II elongation near the poly(A) site of protein-coding genes reveals an additional level of complexity in the modulation of eukaryotic transcriptional elongation and termination. © 2015 Nature America, Inc. All rights reserved. Fil:Giono, L.E. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. Fil:Kornblihtt, A.R. Universidad de Buenos Aires. Facultad de Ciencias Exactas y Naturales; Argentina. 2015 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15459993_v22_n5_p353_Giono http://hdl.handle.net/20.500.12110/paper_15459993_v22_n5_p353_Giono
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	cyclin dependent kinase 9 histone messenger RNA precursor polyadenylic acid RNA polymerase II cyclin dependent kinase 9 glyceraldehyde 3 phosphate dehydrogenase Article chromatin structure enzyme activity enzyme inhibition eukaryote histone modification nucleosome polyadenylation priority journal promoter region protein cleavage protein DNA interaction protein function RNA processing signal transduction transcription elongation transcription initiation site transcription regulation transcription termination antagonists and inhibitors biosynthesis drug effects genetic transcription human RNA translation Eukaryota Cyclin-Dependent Kinase 9 Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) Humans Peptide Chain Elongation, Translational Transcription, Genetic
spellingShingle	cyclin dependent kinase 9 histone messenger RNA precursor polyadenylic acid RNA polymerase II cyclin dependent kinase 9 glyceraldehyde 3 phosphate dehydrogenase Article chromatin structure enzyme activity enzyme inhibition eukaryote histone modification nucleosome polyadenylation priority journal promoter region protein cleavage protein DNA interaction protein function RNA processing signal transduction transcription elongation transcription initiation site transcription regulation transcription termination antagonists and inhibitors biosynthesis drug effects genetic transcription human RNA translation Eukaryota Cyclin-Dependent Kinase 9 Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) Humans Peptide Chain Elongation, Translational Transcription, Genetic Giono, Luciana Eugenia Kornblihtt, Alberto Rodolfo A bumpy road for RNA polymerase II
topic_facet	cyclin dependent kinase 9 histone messenger RNA precursor polyadenylic acid RNA polymerase II cyclin dependent kinase 9 glyceraldehyde 3 phosphate dehydrogenase Article chromatin structure enzyme activity enzyme inhibition eukaryote histone modification nucleosome polyadenylation priority journal promoter region protein cleavage protein DNA interaction protein function RNA processing signal transduction transcription elongation transcription initiation site transcription regulation transcription termination antagonists and inhibitors biosynthesis drug effects genetic transcription human RNA translation Eukaryota Cyclin-Dependent Kinase 9 Glyceraldehyde-3-Phosphate Dehydrogenase (Phosphorylating) Humans Peptide Chain Elongation, Translational Transcription, Genetic
description	The identification of a second regulatory checkpoint controlling RNA polymerase II elongation near the poly(A) site of protein-coding genes reveals an additional level of complexity in the modulation of eukaryotic transcriptional elongation and termination. © 2015 Nature America, Inc. All rights reserved.
author	Giono, Luciana Eugenia Kornblihtt, Alberto Rodolfo
author_facet	Giono, Luciana Eugenia Kornblihtt, Alberto Rodolfo
author_sort	Giono, Luciana Eugenia
title	A bumpy road for RNA polymerase II
title_short	A bumpy road for RNA polymerase II
title_full	A bumpy road for RNA polymerase II
title_fullStr	A bumpy road for RNA polymerase II
title_full_unstemmed	A bumpy road for RNA polymerase II
title_sort	bumpy road for rna polymerase ii
publishDate	2015
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_15459993_v22_n5_p353_Giono http://hdl.handle.net/20.500.12110/paper_15459993_v22_n5_p353_Giono
work_keys_str_mv	AT gionolucianaeugenia abumpyroadforrnapolymeraseii AT kornblihttalbertorodolfo abumpyroadforrnapolymeraseii AT gionolucianaeugenia bumpyroadforrnapolymeraseii AT kornblihttalbertorodolfo bumpyroadforrnapolymeraseii
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A bumpy road for RNA polymerase II

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