Promiscuous behavior of Rhizomucor miehei lipase in the synthesis of N-substituted β-amino esters

A mild and efficient procedure for the aza-Michael addition of amines to acrylates by using lipases as catalysts is reported. Various lipases, mono- and bifunctional amines, alkyl acrylates, and reaction parameters were studied. Under the optimal conditions, Rhizomucor miehei lipase showed high sele...

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Autores principales: Monsalve, Leandro Nicolás, Baldessari, Alicia
Publicado: 2012
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_1434193X_v_n6_p1164_Monsalve
http://hdl.handle.net/20.500.12110/paper_1434193X_v_n6_p1164_Monsalve
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