Intrarenal renin-angiotensin system contributes to tubular acidification adaptation following uninephrectomy

Background/Aims: Reduction in renal mass by uninephrectomy induces a functional compensation in the remnant kidney. The activity of the angiotensin-converting enzyme (ACE) as well as renin mRNA in the proximal convoluted tubule (PCT) of uninephrectomized (UNx) rats increases. The aim of this work wa...

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Detalles Bibliográficos
Publicado:	2001
Materias:	Angiotensin Converting enzyme Micropuncture Na+-H+ Proximal tubular acidification Renin-angiotensin system Uninephrectomy dipeptidyl carboxypeptidase losartan messenger RNA ramipril acidification adaptation animal experiment animal model animal tissue article body fluid brush border vesicle controlled study enzyme activity homeostasis kidney proximal tubule male nonhuman pH priority journal punch biopsy rat renin angiotensin aldosterone system uninephrectomy Acids Adaptation, Physiological Angiotensin-Converting Enzyme Inhibitors Animals Kidney Kidney Tubules, Proximal Losartan Male Nephrectomy Postoperative Period Ramipril Rats Rats, Wistar Receptor, Angiotensin, Type 1 Receptor, Angiotensin, Type 2 Receptors, Angiotensin Renin-Angiotensin System
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10187782_v9_n1_p60_Amorena http://hdl.handle.net/20.500.12110/paper_10187782_v9_n1_p60_Amorena
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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