Comparation of liposomal formulations of ALA Undecanoyl ester for its use in photodynamic therapy

ALA administration has been used to induce the endogenous photosensitiser Protoporphyrin IX for photodynamic therapy (PDT) of tumours. However, the hydrophilic nature of ALA limits its ability to penetrate through skin restricting the use of ALA-PDT to superficial diseases. Lipophilic derivatives of...

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Detalles Bibliográficos
Autores principales: Fukuda, Haydeé, Rodríguez, Lorena Gabriela, Mamone, Leandro A., Casas, Adriana Gabriela, Batlle, Alcira María del Carmen
Publicado: 2009
Materias:
ALA
ALA esters
Aminolevulinic acid
Liposomes
PDT
Photodynamic therapy
aminolevulinic acid
aminolevulinic acid undecanoyl ester
liposome
phosphatidic acid
phosphatidylcholine
phosphatidylglycerol
polymer
porphyrin
porphyrin derivative
unclassified drug
animal cell
animal experiment
animal model
animal tissue
article
breast tumor
cell membrane
controlled study
drug cytotoxicity
drug efficacy
endocytosis
hydrophilicity
lipophilicity
male
membrane binding
mouse
nonhuman
photodynamic therapy
priority journal
skin tumor
tumor cell
Administration, Topical
Aminolevulinic Acid
Animals
Cell Line, Tumor
Ethers
Injections, Subcutaneous
Male
Mice
Photochemotherapy
Photosensitizing Agents
Porphyrins
Mus
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_10111344_v96_n2_p152_Venosa
http://hdl.handle.net/20.500.12110/paper_10111344_v96_n2_p152_Venosa
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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