C/EBP2 mediates growth hormone-regulated expression of multiple target genes

Regulation of c-Fos transcription by GH is mediated by CCAAT/enhancer binding protein β (C/EBPβ). This study examines the role of C/EBPβ in mediating GH activation of other early response genes, including Cyr61, Btg2, Socs3, Zfp36, and Socs1. C/EBPβ depletion using short hairpin RNA impaired respons...

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Guardado en:
Detalles Bibliográficos
Publicado: 2011
Materias:
CCAAT enhancer binding protein beta
cyclic AMP responsive element binding protein
growth hormone
mitogen activated protein kinase
protein p300
short hairpin RNA
STAT protein
1,3 butadiene derivative
1,4 diamino 1,4 bis(2 aminophenylthio) 2,3 dicyanobutadiene
Cebpb protein, mouse
histone acetyltransferase PCAF
nitrile
small interfering RNA
animal cell
article
early response gene
enzyme activation
gene activation
gene expression
gene expression regulation
gene targeting
human
human cell
mouse
nonhuman
oncogene c fos
priority journal
promoter region
protein phosphorylation
animal
cell line
chromatin immunoprecipitation
Cricetulus
DNA responsive element
genetics
hamster
immunoblotting
metabolism
mutation
oncogene
phosphorylation
polymerase chain reaction
signal transduction
transcription initiation
Animals
Butadienes
CCAAT-Enhancer-Binding Protein-beta
Cell Line
Chromatin Immunoprecipitation
Cricetinae
Extracellular Signal-Regulated MAP Kinases
Gene Expression Regulation
Genes, fos
Growth Hormone
Immunoblotting
Mice
Mutation
Nitriles
p300-CBP Transcription Factors
Phosphorylation
Polymerase Chain Reaction
Promoter Regions, Genetic
Response Elements
RNA, Small Interfering
Signal Transduction
Transcriptional Activation
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_08888809_v25_n4_p681_Cui
http://hdl.handle.net/20.500.12110/paper_08888809_v25_n4_p681_Cui
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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