Diurnal Variations of Benzodiazepine Binding in Rat Cerebral Cortex: Disruption by Pinealectomy

In a previous work, pinealectomy was found to depress benzodiazepine (BZP) receptor binding in cerebral cortex membranes of rats killed at noon. In order to assess the effect of pineal removal on diurnal variations of BZP binding site concentration and affinity, groups of intact, pinealectomized, or...

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Guardado en:
Detalles Bibliográficos
Publicado: 1986
Materias:
brain benzodiazepine binding
diurnal rhythms
melatonin
pineal gland
pinealectomy
benzodiazepine receptor
flunitrazepam
radioisotope
animal cell
animal experiment
autopsy
brain cortex
central nervous system
circadian rhythm
drug administration
drug binding
drug receptor binding
flunitrazepam h 3
methodology
nonhuman
pharmacokinetics
rat
Animal
Cerebral Cortex
Circadian Rhythm
Dose-Response Relationship, Drug
Flunitrazepam
Male
Melatonin
Membranes
Pineal Gland
Rats
Receptors, GABA-A
Support, Non-U.S. Gov't
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07423098_v3_n2_p101_Acuna‐Castroviejo
http://hdl.handle.net/20.500.12110/paper_07423098_v3_n2_p101_Acuna‐Castroviejo
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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