Chemiluminescence production by neutrophils and immune complex levels in cancer patients

We studied the production of chemiluminescence (CL) by peripheral blood neutrophils from 24 normal subjects, 13 lung cancer patients with clinical stages (CS) III and IV, and 27 breast cancer patients with CS II, III, and IV. Evaluations were made before chemo- and radiotherapy treatments. CL was ex...

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Publicado:	1993
Materias:	endogenous compound zymosan antigen antibody complex article breast cancer chemoluminescence clinical article controlled study female human human cell lung cancer male neutrophil Antigen-Antibody Complex Breast Neoplasms Chemiluminescence Human Lung Neoplasms Neutrophils Opsonins Oxygen Polyethylene Glycols Zymosan
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07357907_v11_n5_p517_Chasseing http://hdl.handle.net/20.500.12110/paper_07357907_v11_n5_p517_Chasseing
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

id	paper:paper_07357907_v11_n5_p517_Chasseing
record_format	dspace
spelling	paper:paper_07357907_v11_n5_p517_Chasseing2023-06-08T15:44:08Z Chemiluminescence production by neutrophils and immune complex levels in cancer patients endogenous compound zymosan antigen antibody complex article breast cancer chemoluminescence clinical article controlled study female human human cell lung cancer male neutrophil Antigen-Antibody Complex Breast Neoplasms Chemiluminescence Human Lung Neoplasms Neutrophils Opsonins Oxygen Polyethylene Glycols Zymosan We studied the production of chemiluminescence (CL) by peripheral blood neutrophils from 24 normal subjects, 13 lung cancer patients with clinical stages (CS) III and IV, and 27 breast cancer patients with CS II, III, and IV. Evaluations were made before chemo- and radiotherapy treatments. CL was expressed as: baseline of the record background activity; area under the curve (AUC) of opsonized zymosan response; maximum peak (MP) response; time to MP (TMP); and total time (TT). Simultaneously, circulating immune complexes (CIC) in sera were evaluated by polyethylene glycol precipitation technique. The results demonstrated that lung cancer patients with CS III had an increase of TMP and TT values, while breast cancer patients with CS IV showed the lowest values of AUC and MP compared with the control group. The CIC levels were increased in all the cancer patients. There was no correlation between the baseline CL activity and the levels of immune complexes. © 1993 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted. 1993 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07357907_v11_n5_p517_Chasseing http://hdl.handle.net/20.500.12110/paper_07357907_v11_n5_p517_Chasseing
institution	Universidad de Buenos Aires
institution_str	I-28
repository_str	R-134
collection	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic	endogenous compound zymosan antigen antibody complex article breast cancer chemoluminescence clinical article controlled study female human human cell lung cancer male neutrophil Antigen-Antibody Complex Breast Neoplasms Chemiluminescence Human Lung Neoplasms Neutrophils Opsonins Oxygen Polyethylene Glycols Zymosan
spellingShingle	endogenous compound zymosan antigen antibody complex article breast cancer chemoluminescence clinical article controlled study female human human cell lung cancer male neutrophil Antigen-Antibody Complex Breast Neoplasms Chemiluminescence Human Lung Neoplasms Neutrophils Opsonins Oxygen Polyethylene Glycols Zymosan Chemiluminescence production by neutrophils and immune complex levels in cancer patients
topic_facet	endogenous compound zymosan antigen antibody complex article breast cancer chemoluminescence clinical article controlled study female human human cell lung cancer male neutrophil Antigen-Antibody Complex Breast Neoplasms Chemiluminescence Human Lung Neoplasms Neutrophils Opsonins Oxygen Polyethylene Glycols Zymosan
description	We studied the production of chemiluminescence (CL) by peripheral blood neutrophils from 24 normal subjects, 13 lung cancer patients with clinical stages (CS) III and IV, and 27 breast cancer patients with CS II, III, and IV. Evaluations were made before chemo- and radiotherapy treatments. CL was expressed as: baseline of the record background activity; area under the curve (AUC) of opsonized zymosan response; maximum peak (MP) response; time to MP (TMP); and total time (TT). Simultaneously, circulating immune complexes (CIC) in sera were evaluated by polyethylene glycol precipitation technique. The results demonstrated that lung cancer patients with CS III had an increase of TMP and TT values, while breast cancer patients with CS IV showed the lowest values of AUC and MP compared with the control group. The CIC levels were increased in all the cancer patients. There was no correlation between the baseline CL activity and the levels of immune complexes. © 1993 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
title	Chemiluminescence production by neutrophils and immune complex levels in cancer patients
title_short	Chemiluminescence production by neutrophils and immune complex levels in cancer patients
title_full	Chemiluminescence production by neutrophils and immune complex levels in cancer patients
title_fullStr	Chemiluminescence production by neutrophils and immune complex levels in cancer patients
title_full_unstemmed	Chemiluminescence production by neutrophils and immune complex levels in cancer patients
title_sort	chemiluminescence production by neutrophils and immune complex levels in cancer patients
publishDate	1993
url	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07357907_v11_n5_p517_Chasseing http://hdl.handle.net/20.500.12110/paper_07357907_v11_n5_p517_Chasseing
_version_	1768545883536752640

Chemiluminescence production by neutrophils and immune complex levels in cancer patients

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