Adrenal gland involvement in the regulation of renal 11 β-hydroxysteroid dehydrogenase 2
Renal 11 β-hydroxysteroid dehydrogenase 2 (HSD2) catalyzes the conversion of active glucocorticoids to inert 11 β-keto compounds, thereby preventing the illicit binding of these hormones to mineralocorticoid receptors (MRs) and, thus, conferring aldosterone specificity. Absence or inhibition of HSD2...
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| Autores principales: | , , |
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2004
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| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_07302312_v92_n3_p591_Zallocchi http://hdl.handle.net/20.500.12110/paper_07302312_v92_n3_p591_Zallocchi |
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