Extracellular ATP and bradykinin increase cGMP in vascular endothelial cells via activation of PKC

Vasodilation by agents such as bradykinin and ATP is dependent on nitric oxide, the endothelium-dependent relaxing factor (EDRF). The release of EDRF results in elevation of cGMP in endothelial and smooth muscle cells (9). The signaling pathway that leads to increases in cGMP is not completely under...

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Guardado en:
Detalles Bibliográficos
Publicado: 1998
Materias:
Endothelium-dependent relaxing factor
Phorbol ester
Protein kinase C inhibitors
adenosine triphosphate
bradykinin
calphostin c
cremophor
cyclic gmp
guanylate cyclase
nitric oxide
nitroprusside sodium
phorbol 13 acetate 12 myristate
phorbol ester derivative
protein kinase c
protein kinase c inhibitor
staurosporine
animal cell
article
controlled study
endothelium cell
enzyme activation
enzyme activity
immunoblotting
nonhuman
polyacrylamide gel electrophoresis
priority journal
protein phosphorylation
radioimmunoassay
swine
vascular endothelium
Adenosine Triphosphate
Animals
Aorta, Thoracic
Bradykinin
Cells, Cultured
Cyclic GMP
Endothelium, Vascular
Enzyme Activation
Enzyme Inhibitors
Fetus
Kinetics
Naphthalenes
NG-Nitroarginine Methyl Ester
Nitric Oxide
Phorbol Esters
Polyethylene Glycols
Protein Kinase C
Staurosporine
Swine
Tetradecanoylphorbol Acetate
Time Factors
Vasodilator Agents
Animalia
Suidae
Sus scrofa
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03636143_v275_n144-1_pC113_Castro
http://hdl.handle.net/20.500.12110/paper_03636143_v275_n144-1_pC113_Castro
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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