Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects

Intimal hyperplasia development is recognized as the most important cause of vascular access failure in patients submitted renal function replacement therapy. An important factor that affects the development of intimal hyperplasia is elastic mismatch between native vessel and among vein, arteries an...

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Publicado: 2005
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03263428_v25_n4_p141_Zocalo
http://hdl.handle.net/20.500.12110/paper_03263428_v25_n4_p141_Zocalo
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spelling paper:paper_03263428_v25_n4_p141_Zocalo2023-06-08T15:33:04Z Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects politef arterial pressure artery diameter article biomechanics blood vessel compliance blood vessel parameters controlled study cryopreservation elasticity hemodialysis hemodialysis patient human human tissue in vitro study pneumatic tool politef implant treatment outcome ultrasound vascular access vein diameter venous pressure Intimal hyperplasia development is recognized as the most important cause of vascular access failure in patients submitted renal function replacement therapy. An important factor that affects the development of intimal hyperplasia is elastic mismatch between native vessel and among vein, arteries and the synthetic graft. In this work, a biomechanical analysis of cryopreserved arteries, expanded polytetrafluoroethylene (ePTFE), and fresh arteries and veins is reported. In vitro pressure (Konigsberg) and diameter (Sonomicrometry) were measured in fresh human vein and arteries and cryopreserved human defrosted arteries and ePTFE prosthesis, under isobaric and systemic pressures levels. Our results showed that ePTFE conduits have an elastic index which is significantly different from that of fresh and cryopreserved defrosted arteries and veins. These stiffness differences determine a high elastic mismatch. We conclude that this study of tubular segments to be used as vascular accesses in dialyzed patients, demonstrate significantly elastic differences that could be an important determinant of late access viability. 2005 https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03263428_v25_n4_p141_Zocalo http://hdl.handle.net/20.500.12110/paper_03263428_v25_n4_p141_Zocalo
institution Universidad de Buenos Aires
institution_str I-28
repository_str R-134
collection Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA)
topic politef
arterial pressure
artery diameter
article
biomechanics
blood vessel compliance
blood vessel parameters
controlled study
cryopreservation
elasticity
hemodialysis
hemodialysis patient
human
human tissue
in vitro study
pneumatic tool
politef implant
treatment outcome
ultrasound
vascular access
vein diameter
venous pressure
spellingShingle politef
arterial pressure
artery diameter
article
biomechanics
blood vessel compliance
blood vessel parameters
controlled study
cryopreservation
elasticity
hemodialysis
hemodialysis patient
human
human tissue
in vitro study
pneumatic tool
politef implant
treatment outcome
ultrasound
vascular access
vein diameter
venous pressure
Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects
topic_facet politef
arterial pressure
artery diameter
article
biomechanics
blood vessel compliance
blood vessel parameters
controlled study
cryopreservation
elasticity
hemodialysis
hemodialysis patient
human
human tissue
in vitro study
pneumatic tool
politef implant
treatment outcome
ultrasound
vascular access
vein diameter
venous pressure
description Intimal hyperplasia development is recognized as the most important cause of vascular access failure in patients submitted renal function replacement therapy. An important factor that affects the development of intimal hyperplasia is elastic mismatch between native vessel and among vein, arteries and the synthetic graft. In this work, a biomechanical analysis of cryopreserved arteries, expanded polytetrafluoroethylene (ePTFE), and fresh arteries and veins is reported. In vitro pressure (Konigsberg) and diameter (Sonomicrometry) were measured in fresh human vein and arteries and cryopreserved human defrosted arteries and ePTFE prosthesis, under isobaric and systemic pressures levels. Our results showed that ePTFE conduits have an elastic index which is significantly different from that of fresh and cryopreserved defrosted arteries and veins. These stiffness differences determine a high elastic mismatch. We conclude that this study of tubular segments to be used as vascular accesses in dialyzed patients, demonstrate significantly elastic differences that could be an important determinant of late access viability.
title Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects
title_short Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects
title_full Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects
title_fullStr Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects
title_full_unstemmed Characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects
title_sort characterization of the mechanic behavior of the conduits used in the confection of vascular accesses in dialyzed subjects
publishDate 2005
url https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03263428_v25_n4_p141_Zocalo
http://hdl.handle.net/20.500.12110/paper_03263428_v25_n4_p141_Zocalo
_version_ 1768543753021161472