β-adrenergic control of the water permeability of the skin during rehydration in the toad Bufo arenarum

1. Toads dehydrated to 80% of their standard weight (% SW) were rehydrated during 3 hr in distilled water. 2. Water permeability of the skin was positively correlated with the degree of dehydration in the range 80-100% SW. 3. Systemic administration of the β-adrenergic agonist isoproterenol (5 mg/kg...

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Publicado: 1991
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_03064492_v100_n3_p433_Reboreda
http://hdl.handle.net/20.500.12110/paper_03064492_v100_n3_p433_Reboreda
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Sumario:1. Toads dehydrated to 80% of their standard weight (% SW) were rehydrated during 3 hr in distilled water. 2. Water permeability of the skin was positively correlated with the degree of dehydration in the range 80-100% SW. 3. Systemic administration of the β-adrenergic agonist isoproterenol (5 mg/kg) 90 min after rehydration started (animals fully hydrated) increased skin permeability to the values observed in 80% SW dehydrated animals. 4. The administration of the β-adrenergic blocker propranolol (5 mg/kg) 15 min before rehydration started produced a long-lasting decrease in water permeability during the 3 hr of rehydration. 5. The results are consistent with the hypothesis of a β-adrenergic control of the water permeability of the skin during rehydration. © 1991.