Sam68 mediates leptin-stimulated growth by modulating leptin receptor signaling in human trophoblastic JEG-3 cells

Background Sam68, a member of the signal transduction and activation of RNA metabolism (STAR) family of RNA-binding proteins, has been previously implicated as an adaptor molecule in different signaling systems, including leptin receptor (LEPR) signaling. LEPR activation is known to stimulate JAK-ST...

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Detalles Bibliográficos
Autor principal: Varone, Cecilia Laura
Publicado: 2011
Materias:
LEPR signaling
leptin
placenta
Sam68
trophoblast
DNA
Janus kinase 2
leptin receptor
leucine
mitogen activated protein kinase
phosphatidylinositol 3 kinase
protein Sam68
STAT3 protein
tyrosine
article
cell growth
cell proliferation
controlled study
DNA synthesis
down regulation
enzyme activation
gene overexpression
human
human cell
human cell culture
immunoblotting
immunoprecipitation
protein expression
protein phosphorylation
protein protein interaction
protein synthesis
signal transduction
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_02681161_v26_n9_p2306_SanchezJimenez
http://hdl.handle.net/20.500.12110/paper_02681161_v26_n9_p2306_SanchezJimenez
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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