Inhibition of cytochrome P-450 C17 enzyme by a GnRH agonist in ovarian follicles from gonadotropin-stimulated rats

Our objective was to study the direct action of a GnRH-I agonist, leuprolide acetate (LA), on ovarian steroidogenesis in preovulatory follicles obtained from equine chorionic gonadotropin (eCG)-treated rats. Previously, we have demonstrated an inhibitory effect of LA on steroidogenesis and follicula...

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Detalles Bibliográficos
Publicado:	2007
Materias:	Follicle Gonadotropin-releasing hormone agonist Ovary Steroidogenesis androgen androsterone cytochrome P450 gonadorelin gonadorelin agonist gonadotropin leuprorelin steroidogenic acute regulatory protein animal experiment article controlled study enzyme inhibition female gene expression immunohistochemistry nonhuman ovary follicle priority journal progesterone blood level rat reverse transcription polymerase chain reaction steroidogenesis Western blotting Androsterone Animals Blotting, Western Female Gonadotropin-Releasing Hormone Gonadotropins, Equine Horses Immunohistochemistry Leuprolide Ovarian Follicle Phosphoproteins Progesterone Rats Rats, Sprague-Dawley Reverse Transcriptase Polymerase Chain Reaction RNA Steroid 17-alpha-Hydroxylase
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_01931849_v292_n5_pE1456_Irusta http://hdl.handle.net/20.500.12110/paper_01931849_v292_n5_pE1456_Irusta
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

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