Synthesis and antifungal activity of C-21 steroids with an aromatic D ring
Six analogues of salpichrolides with a simplified side chain (6-11) were synthesized using a new methodology to obtain steroids with an aromatic D-ring. The key step was the elimination of HBr in a vicinal dibromo D-homosteroid by treatment with 1,4-diazabicyclo[2.2.2]octane (DABCO). All new compoun...
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| Autores principales: | Sonego, Juan Manuel, Cirigliano, Adriana Mónica, Cabrera, Gabriela Myriam, Burton, Gerardo, Veleiro, Adriana Silvia |
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| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_0039128X_v78_n7_p644_Sonego http://hdl.handle.net/20.500.12110/paper_0039128X_v78_n7_p644_Sonego |
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