Glomerulopressin Production by Isolated Rat Liver after Amino Acid Infusion

The infusion of certain amino acids, such as serine, alanine, and proline (SAP), has been shown to increase the glomerular filtration rate, whereas branched chain amino acids (BCAA) leucine, isoleucine, and valine fail to modify the glomerular filtration rate. It has been suggested that this effect...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado: 1991
Materias:
amino acid
glomerulopressin
unclassified drug
animal cell
article
controlled study
glomerulus filtration rate
liver cell
male
nonhuman
priority journal
rat
Alanine
Amino Acids
Amino Acids, Branched-Chain
Analysis of Variance
Animal
Dinoprostone
Dose-Response Relationship, Drug
Female
Glucuronates
Infusions, Intravenous
Liver
Male
Muscle Tonus
Muscle, Smooth
Proline
Rats
Rats, Inbred Strains
Serine
Support, Non-U.S. Gov't
Animalia
Glomerulus
Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00379727_v198_n1_p625_Silberstein
http://hdl.handle.net/20.500.12110/paper_00379727_v198_n1_p625_Silberstein
Aporte de:
Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires
Descripción
Sumario:The infusion of certain amino acids, such as serine, alanine, and proline (SAP), has been shown to increase the glomerular filtration rate, whereas branched chain amino acids (BCAA) leucine, isoleucine, and valine fail to modify the glomerular filtration rate. It has been suggested that this effect of amino acids on the glomerular filtration rate is mediated by the action of the hormone glomerulopressin. The purpose of this work was to study the action of SAP and BCAA on glomerulopressin production. Livers isolated from rats were perfused with (i) Krebs-Ringer-Bicarbonate, (ii) SAP, or (iii) BCAA. Results indicate that glomerulopressin production is stimulated by SAP, but inhibited by BCAA. © 1991, SAGE Publications. All rights reserved.

Ejemplares similares