Antimicrobial metabolites produced by an intertidal Acremonium furcatum

In a screening for antimicrobial metabolites, amides of d-allo- and l-isoleucine derivatives were isolated from the culture of a marine strain of Acremonium furcatum. Structural elucidation of these compounds was performed by analysis of spectroscopic data and confirmed by synthesis. All of the comp...

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Autores principales: Gallardo, Gabriela Laura, Butler, Matìas, Gallo, Mariana, Rodríguez, María Alejandra, Cabrera, Gabriela Myriam
Publicado: 2006
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Acceso en línea:https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00319422_v67_n21_p2403_Gallardo
http://hdl.handle.net/20.500.12110/paper_00319422_v67_n21_p2403_Gallardo
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Sumario:In a screening for antimicrobial metabolites, amides of d-allo- and l-isoleucine derivatives were isolated from the culture of a marine strain of Acremonium furcatum. Structural elucidation of these compounds was performed by analysis of spectroscopic data and confirmed by synthesis. All of the compounds, natural and synthetic intermediates, were bioassayed against bacteria and phytopathogenic fungi, with many showing remarkable antifungal activities. © 2006 Elsevier Ltd. All rights reserved.