Heparin cofactor II, a thrombin inhibitor with a still unclarified physiologic role

Heparin Cofactor II (HCII) is a glycoprotein in human plasma which inactivates thrombin rapidly in the presence of dermatan sulfate. Inhibition occurs by formation of a stable equimolar complex between HCII and thrombin. HCII association with thrombotic events has not always been observed, thus decr...

Descripción completa

Guardado en:

Detalles Bibliográficos
Publicado:	1999
Materias:	Dermatan sulfate Heparin cofactor II Thrombin dermatan sulfate heparin heparin cofactor thrombin anticoagulation article burn human hyperhomocysteinemia liver failure nerve cell differentiation risk factor sepsis sickle cell anemia thalassemia thromboembolism wound healing Coagulation Protein Disorders Dermatan Sulfate Heparin Cofactor II Humans Reference Values Serine Proteinase Inhibitors
Acceso en línea:	https://bibliotecadigital.exactas.uba.ar/collection/paper/document/paper_00257680_v59_n1_p95_Rossi http://hdl.handle.net/20.500.12110/paper_00257680_v59_n1_p95_Rossi
Aporte de:	Biblioteca Digital - Facultad de Ciencias Exactas y Naturales (UBA) de Universidad de Buenos Aires

Ejemplares similares

Heparin cofactor II, a thrombin inhibitor with a still unclarified physiologic role
por: Rossi, E.B., et al.

Niveles plasmáticos e interacciones del sistema cofactor 2 de la heparina-trombina-dermatan sulfato
por: Rossi, Eleonora Beatriz
Publicado: (1999)

Niveles plasmáticos e interacciones del sistema cofactor 2 de la heparina-trombina-dermatan sulfato
por: Rossi, Eleonora Beatriz
Publicado: (1999)

Niveles plasmáticos e interacciones del sistema cofactor 2 de la heparina-trombina-dermatan sulfato
por: Rossi, Eleonora Beatriz
Publicado: (1999)

Heparin cofactor II in diabetic patients
Publicado: (1994)

Heparin cofactor II in diabetic patients
por: Duboscq, C., et al.

Isolation of a small fraction of dermatan sulfate with potential therapeutical application
por: Recondo, Eduardo Francisco
Publicado: (2005)

Isolation of a small fraction of dermatan sulfate with potential therapeutical application
por: Recondo, E.F., et al.

Dermatan sulfate synergizes with heparin in murine sperm chromatin decondensation
por: Julianelli, Vanina Laura, et al.
Publicado: (2013)

Dermatan sulfate synergizes with heparin in murine sperm chromatin decondensation
por: Sanchez, M.C., et al.
Publicado: (2013)

Dermatan sulfate synergizes with heparin in murine sperm chromatin decondensation
por: Sanchez, M.C., et al.

Dermatan sulfate synergizes with heparin in murine sperm chromatin decondensation
por: Sanchez, M.C., et al.
Publicado: (2013)

La descondensación de la cromatina de espermatozoides de mamíferos : estudio de su mecanismo molecular y su posible utilidad como bioindicador del efecto de disruptores endócrinos
por: Sánchez, Melisa Celeste
Publicado: (2016)

La descondensación de la cromatina de espermatozoides de mamíferos : estudio de su mecanismo molecular y su posible utilidad como bioindicador del efecto de disruptores endócrinos
por: Sánchez, Melisa Celeste
Publicado: (2016)

La descondensación de la cromatina de espermatozoides de mamíferos : estudio de su mecanismo molecular y su posible utilidad como bioindicador del efecto de disruptores endócrinos
por: Sánchez, Melisa Celeste
Publicado: (2016)

A small fraction of dermatan sulfate with significantly increased anticoagulant activity was selected by interaction with the first complement protein
por: Recondo, Eduardo Francisco
Publicado: (2004)

A small fraction of dermatan sulfate with significantly increased anticoagulant activity was selected by interaction with the first complement protein
por: Calabrese, G.C., et al.

Heparan sulphate: A putative decondensing agent for human spermatozoa in vivo
Publicado: (2003)

Heparan sulphate: A putative decondensing agent for human spermatozoa in vivo
por: Romanato, M., et al.

Overview of anticoagulant activity of sulfated polysaccharides from seaweeds in relation to their structures, focusing on those of green seaweeds
por: Ciancia, Marina

Overview of anticoagulant activity of sulfated polysaccharides from seaweeds in relation to their structures, focusing on those of green seaweeds
por: Ciancia, Marina

Further evidence for the critical role of a non-chair conformation of L-iduronic acid in the activation of antithrombin
Publicado: (2002)

Further evidence for the critical role of a non-chair conformation of L-iduronic acid in the activation of antithrombin
por: Kovensky, J., et al.

Overview of anticoagulant activity of sulfated polysaccharides from seaweeds in relation to their structures, focusing on those of green seaweeds
por: Ciancia, Marina, et al.
Publicado: (2010)

Overview of anticoagulant activity of sulfated polysaccharides from seaweeds in relation to their structures, focusing on those of green seaweeds
por: Ciancia, M., et al.

Anticoagulant activity of a unique sulfated pyranosic (1→3)-β-L- arabinan through direct interaction with thrombin
por: Fernández, Paula Virginia, et al.
Publicado: (2013)

Anticoagulant activity of a unique sulfated pyranosic (1→3)-β-L- arabinan through direct interaction with thrombin
por: Fernández, P.V., et al.
Publicado: (2013)

Anticoagulant activity of a unique sulfated pyranosic (1→3)-β-L- arabinan through direct interaction with thrombin
por: Fernández, P.V., et al.

Anticoagulant activity of a unique sulfated pyranosic (1→3)-β-L- arabinan through direct interaction with thrombin
por: Fernández, P.V., et al.
Publicado: (2013)

Insight into the profibrinolytic activity of dermatan sulfate: Effects on the activation of plasminogen mediated by tissue and urinary plasminogen activators
por: Castañon, María Mercedes, et al.
Publicado: (2007)

Insight into the profibrinolytic activity of dermatan sulfate: Effects on the activation of plasminogen mediated by tissue and urinary plasminogen activators
por: Castañon, M.M., et al.

Heparin-induced thrombocytopenia /
Publicado: (2013)

A suitable method for a rapid estimation of sulphated positions in polysaccharides of pharmacological interest
por: Kovensky, José Eduardo, et al.
Publicado: (1990)

A suitable method for a rapid estimation of sulphated positions in polysaccharides of pharmacological interest
por: Kovensky, J., et al.

Heparan sulfate, heparin, and heparinase activity detection on polyacrylamide gel electrophoresis using the fluorochrome tris(2,2′-bipyridine) ruthenium
Publicado: (2001)

Heparan sulfate, heparin, and heparinase activity detection on polyacrylamide gel electrophoresis using the fluorochrome tris(2,2′-bipyridine) ruthenium
por: Rozenberg, G.I., et al.

Low anticoagulant activity of high sulphated heparan sulphates
por: Kovensky, José Eduardo, et al.
Publicado: (1990)

Low anticoagulant activity of high sulphated heparan sulphates
por: Kovensky, J., et al.

Heparin increases the adhesion of murine mammary adenocarcinoma cells (LM3). Correlation with the presence of heparin receptors on cell surface
por: Bertolesi, Gabriel Esteban, et al.
Publicado: (2005)

Heparin increases the adhesion of murine mammary adenocarcinoma cells (LM3). Correlation with the presence of heparin receptors on cell surface
por: Bertolesi, G., et al.